Psilocybe tampanensis is a very rare psychedelic mushroom in the Strophariaceae family. Originally collected in the wild in a sandy meadow near Tampa, Florida in 1977, the fungus has never again been reported in Florida, but was later collected in Mississippi. The original Florida specimen was cloned, and descendents remain in wide circulation. The fruit bodies (mushrooms) produced by the fungus are yellowish-brown in color with convex to conic caps up to 2.4 cm (0.9 in) in diameter atop a thin stem up to 6 cm (2.4 in) long. Psilocybe tampanensis forms psychoactive truffle-like sclerotia that are known and sold under the nickname "philosopher's stones". The fruit bodies and sclerotia are consumed by some for recreational or entheogenic purposes. In nature, sclerotia are produced by the fungus as a form of protection from wildfires and other natural disasters.
Psilocybe tampanensis contains the psychedelic compounds psilocin and psilocybin, and is consumed for recreational and entheogenic purposes. The species was found to be one of the most popular psychoactive mushrooms confiscated by German authorities in a 2000 report, behind Psilocybe cubensis, Psilocybe semilanceata, and Panaeolus cyanescens. The alkaloid content in the confiscated samples ranged from not detectable to 0.19% psilocybin, and 0.01 to 0.03% psilocin. According to mycologist Michael Beug, dried fruit bodies can contain up to 1% psilocybin and psilocin; in terms of psychoactive potency, Stamets considers the mushroom "moderately to highly active".The psychoactive compounds are also present in the sclerotia: in one analysis, the levels of psilocybin obtained from sclerotia ranged from 0.31% to 0.68% by dry weight, and were dependent upon the composition of the growth medium.Sclerotia are sold under the nickname "philosopher's stones". They have been described as "resembling congealed muesli", and having a somewhat bitter taste similar to walnut. Strains existing as commercial cultivation kits sold originally in countercultural drug magazines are derived from the original fruit body found by Pollock in Florida.Methods were originally developed by Pollock, and later extended by Stamets in the 1980s to cultivate the sclerotia on a substrate of rye grass (Lolium), and on straw. Sclerotia prepared in this way take from 3 to 12 weeks to develop. Pollock was granted a US patent in 1981 for his method of producing sclerotia
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